How alcohol can interact with GLP-1 medications
Here's the good news: most people can enjoy moderate amounts of alcohol while taking GLP-1 medications, but there are some important things to consider to keep yourself safe and feeling good.
Blood Sugar Levels
GLP-1 medications such as Wegovy help regulate blood sugar levels by slowing digestion and reducing glucose release into the bloodstream [1].
Alcohol can disrupt this balance, depending on the type of beverage, the quantity consumed, and individual factors [2, 4]:
- Alcohol can lead to hypoglycemia (low blood sugar). The liver is responsible for breaking down alcohol, and when it does, it may reduce its glucose production. This, in combination with the blood sugar-lowering effects of GLP-1 medications can make your blood sugar drop too low (especially if you're taking other diabetes medications), making it dangerous.
- Sugary cocktails can spike your blood sugar up, as well as excessive alcohol intake.
- Alcohol can also stimulate appetite, leading to overeating.
Gastrointestinal Side Effects:
GLP-1 medications often cause side effects like nausea, vomiting, or acid reflux [3]. Alcohol, especially in larger quantities, can worsen these symptoms, making you feel more uncomfortable.
Weight Loss Goals:
GLP-1 medications are often prescribed as part of a weight loss plan. Alcohol is calorie-dense and provides little nutritional value, which can hinder your progress if consumed frequently or in large quantities. Plus, it could also make you hungry for late-night snacks!
Guidelines for drinking alcohol on GLP-1
Moderation Is Key
The Australian National Health and Medical Research Council outlines a standard drink contains 10 grams of pure alcohol. The type of alcohol makes no difference, 10 grams of alcohol is 10 grams of alcohol, whether it is in beer, wine or spirits.
Try to avoid excessive or binge drinking while on GLP-1 medications.
Smart Strategies That Can Help
Before You Drink:
- Eat something! Never drink on an empty stomach
- Stay hydrated (water is your friend!)
- Check your medication timing
Choose Your Drinks Wisely:
- Dry wine is usually a good choice due to less sugar
- Light beer works well as there is lower alcohol content
- Spirits with zero-calorie mixers will have less sugar
- Skip the sugary cocktails
Listen to Your Body:
- Feeling extra queasy? Maybe skip the drink today
- Dizzy or uncomfortable? That's your body talking!
- Keep track of how different drinks make you feel
When to Avoid Alcohol Completely
You should avoid alcohol entirely while taking GLP-1 medications if:
- You have a history of pancreatitis.
- You are taking medications that significantly increase the risk of hypoglycemia.
- You experience severe gastrointestinal symptoms from GLP-1 medication.
- Your practitioner advises against it due to other medical conditions or risks.
Tips for Social Situations
Having a party?
- Volunteer to be the designated driver
- Try mocktails - they can be just as fun! However, just be aware that similar to cocktails, mocktails can be loaded with sugar and hidden calories.
- Keep sparkling water with lime handy (looks like a cocktail!)
At a restaurant?
- Order a single drink and make it last
- Alternate between alcohol and water
- Don't feel pressured to drink just because others are
When to reach out to your Moshy medical team
Reach out to your medical team if you experience:
- Severe nausea or vomiting after drinking
- Unusual dizziness or weakness
- Extreme blood sugar swings
- Any concerning symptoms
You can probably enjoy moderate drinking while taking GLP-1 medications, but the key words are "moderate" and "mindful." When in doubt, start with less than you think you can handle and see how your body responds.
Everyone's body is different! What works for someone else might not work for you. Start slow, pay attention to how you feel, and always prioritise your health and comfort.
Not sure if GLP-1 treatment is right for your lifestyle?
Take Moshy’s free online quiz to see if a medically guided GLP-1 weight loss program is suitable for you. It’s quick, easy, and designed to help you make informed choices with expert support.